Seth Rogen, star of "Knocked Up" and creator of "Superbad," hosts SNL featuring an address by Kevin Federline (Andy Samberg) sharing parenting tips; Seth Rogen's monologue that he wrote at age 13 in the event that he would one day host SNL; HD Ultrasound (commercial parody), a new way for expectant fathers to watch their kids development in high definition; Sharon Osbourne (Amy Poehler), Gene Simmons (Fred Armisen) and Gerard (Andy Samberg) judge The National Douchebag Championship, where contestants compete to show who is most deserving of the title of the biggest douchebag; MacGruber (Will Forte) deals with diffusing bombs in the midst of mid-life crisis plastic surgery; Ugly kids Jeremy and Stacia (Seth Rogen and Kristen Wiig) perform at their parent's dinner party; Fred Thompson (Darrell Hammond) addresses the public regarding his late entry into the 2008 presidential race and takes on rumors that he is lazy; Weekend Update (Seth Meyers and Amy Poehler) featuring Lou Dobbs (Darrell Hammond), Seth and Amy discuss Larry Craig, The New York Mets' Willie Randolph and Omar Minaya (Kenan Thompson and Fred Armisen) and Chevy Chase weighs in on the 2008 presidential race; John Stone and other colonists of Stonetown discover a new plant that they decide to cultivate; and Mad Joe Dixon (Seth Rogen) tells a fair lady (Maya Rudolph) what really turns him on.