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Rose made his debut as an actress at the age of 12 years in the film Dallas Doll (1994), after participating in several Australian television shows and films for television as Two Hands (1999) alongside Heath Ledger. In 2000, back on the big screen with My Mother Frank and The Goddess of '67 (The Goddess of 1967) while in 2002 he starred in City of Ghosts. At the Venice International Film Festival of 2000 receives the Coppa Volpi for Best Actress for the role of BG in The Goddess of '67. Appears in blockbuster Star Wars: Episode II - Attack of the Clones (2002) and in 2003 she starred in The scent of bluebells Tim Fywell. In 2004 plays Briseis in Wolfgang Petersen's film Troy starring Brad Pitt and Orlando Bloom. He recently worked in Sunshine (2007) and horror 28 Weeks Later (2007). Since 2007 he has undertaken the role of Ellen Parsons, the critically acclaimed television series Damages, which also earned a Golden Globe nomination for Best Supporting Actress.

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