NBA basketball star LeBron James hosts the season premiere of Saturday Night Live with musical guest Kanye West. Hillary Clinton (Amy Poehler) looks ahead to winning the presidential election; LeBron James gives a shout out to his family watching at home in Akron, Ohio; Penelope (Kristen Wiig) is yet again out doing everyone in the room, this time at a children's auction; LeBron James shoots a PSA for literacy and has a little trouble with one of the crew guys (Jason Sudeikis); Socially awkward Lyle Kane (Will Forte) hosts a talk show and welcomes guests (LeBron James and Bill Hader); Weekend Update with Seth Meyers and Amy Poehler; TV Funhouse: Ambiguously Gay Duo; Kanye West interrupts several award shows to complain about not winning; LeBron James tells his high school guidance counselor that he's opting to go to college instead of the NBA draft.Sketches include Hillary Cold Open, Lebronologue, Commercial Parody: Dog Food, Penelope Auction, An SNL Digital Short: Iran So Far, Read to Achieve, The Lyle Kane Show, Weekend Update featuring Kenan Thompson, Fred Armisen and Maya Rudolph, TV Funhouse: Ambiguously Gay Duo, 106 & Park, Guidance Counselor.