Wilfred revolves around a man named Ryan, his neighbor Jenna, and her dog Wilfred. Ryan sees Wilfred as a man in a cheap dog suit while everyone else sees Wilfred as a normal dog. Ryan agrees to watch Wilfred and he discovers just what he is made of. Wilfred is a very crude, surly, pot smoking, beer drinking dog, but also speaks his mind to Ryan. Wilfred seems intent on causing chaos for Ryan in any way imaginable. When asked, David Zuckerman (Executive Producer) described Wilfred as a mixed breed dog who is part Labrador retriever and part “Russell Crowe on a bender”.

The cast of Wilfred includes Elijah Wood as Ryan, Jason Gann as Wilfred, Fiona Gubelmann as Jenna, and Dorian Brown as Kristen. The Executive Producers are David Zuckerman, Rich Frank, Paul Frank, Jeff Kwantinez, Joe Connor, and Ken Conner. Wilfred was created by Jason Gann, Adam Zwar and Tony Rogers; and originated in Australia and was being remade in the US for FX.